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Structure Therapeutics Inc.

Stage 4 · Declining · week 6

As of Oct 22, 2026, Structure Therapeutics is in Stage 4, the downtrend phase, now in week 6 (since Sep 16, 2026). It closed at $21.93, 76.6% below its 52-week high and below its 200-day average, which is falling.

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral small molecule therapeutics to treat various chronic diseases with unmet medical needs in the United States. More about the company

$21.93
-1.22% today
$1.6B · Small cap
Market Neutral — Building

Pro read

Pro

Our read

Declining, below its long-term trend

Setup score

—

Momentum

Steady

Edge

—

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Stage Cycle Timeline2023-08-16 → 2026-10-22
S? 13w
S4 25w
S2 22w
2023-08-162026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S? 13w → S2 6w → S3 9w → S4 1w → S3 2w → S4 12w → S1 10w → S4 7w → S1 7w → S4 25w → S1 9w → S4 10w → S1 3w → S2 22w → S3 10w → S4 7w → S1 9w → S4 5w current
Total tracked: 166 weeks across 18 stage runs.

GPCR among Biotechnology246th of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…246GPCRStage 4 · wk 640−39.0%
vs 52W High
-76.6%
$21.08 lo$93.79 hi
76.6% below 52W high, deep Stage 4 damage
In Stage 4, distance from the 52-week high reflects an ongoing decline, not a discount.
Stage Maturity
Week 6
1w13w26w
Week 6, early Stage 4 decline
How long this stock has been in Stage 4 decline. The longer the downtrend, the more entrenched the selling pressure. No length of decline marks a bottom on its own.
vs 200 DMA
-56.6%
200 DMA: $50.58 · sloping down
In Stage 4, the stock is below its 200-day average, the hallmark of a downtrend. Stage analysis waits for that to reverse before buying.
Rel Volume
0.57x
vs 50-day avg
High volume on down days in Stage 4 confirms institutional selling. Low-volume bounces are typical. They lack real buyers and are easy to mistake for reversals.
Trend Health
↓
Short-term trend rolling over
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
-39.0%
3M
-55.4%
6M
-53.4%
YTD
-67.8%
1Y
-18.5%
Scan Membership
Breakout Watch
Latest: 2023-11-17
A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.
Recent Stage Timeline
2026-10-22S4
Wk 6 · Vol 0.57x
2026-10-21S4
Wk 6 · Vol 0.62x
2026-10-20S4
Wk 5 · Vol 1.18x
2026-10-19S4
Wk 5 · Vol 1.11x
2026-10-16S4
Wk 5 · Vol 1.00x
2026-10-15S4
Wk 5 · Vol 1.23x
2026-10-14S4
Wk 5 · Vol 1.84x
2026-10-13S4
Wk 4 · Vol 1.30x
2026-10-12S4
Wk 4 · Vol 1.54x
2026-10-09S4
Wk 4 · Vol 0.55x
2026-10-08S4
Wk 4 · Vol 0.88x
2026-10-07S4
Wk 4 · Vol 1.00x
Moving averages & range
50 DMA
$37.28
200 DMA
$50.58
52W High
$93.79
52W Low
$21.08
5D Low
$21.08
Resistance levels (recent highs)
20d High
$35.93
60d High
$54.70
120d High
$56.63
250d High
$93.79
Next resistance
+63.8%
to 20d High
ROE
-20.2%
Profit margin 0.0%
Dividend Yield
0.00%
P/B 1.2

Structure Therapeutics: quick answers

What stage is Structure Therapeutics in?

As of Oct 22, 2026, Structure Therapeutics (GPCR) is in Stage 4, the downtrend phase. It entered Stage 4 on Sep 16, 2026 and is in week 6. What the four stages mean

Is Structure Therapeutics in an uptrend?

No. Structure Therapeutics is in a Stage 4 downtrend. It trades 56.6% below its 200-day average, which is falling.

How far is Structure Therapeutics from its 52-week high?

Structure Therapeutics closed at $21.93 on Oct 22, 2026, 76.6% below its 52-week high of $93.79. Its 52-week low is $21.08.

How has Structure Therapeutics performed over the past year?

As of Oct 22, 2026, Structure Therapeutics is down 18.5% over the past year and down 67.8% so far in 2026.

Which sector and industry is Structure Therapeutics in?

Structure Therapeutics is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral small molecule therapeutics to treat various chronic diseases with unmet medical needs in the United States. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, which is in two phase 2 clinical trials for the treatment of obesity, overweight, and related conditions. The company also develops ACCG-2671 and ACCG-3535, an oral small molecule amylin receptor agonist that is in phase1 clinical trial for the treatment of obesity; ANPA-0073, an oral small molecule APJ receptor agonist; and LTSE-2578, an antagonist that targets lysophosphatidic acid 1 receptor, a G-protein coupled receptors implicated in responses to tissue injury and pro-fibrotic processes, for the treatment of idiopathic pulmonary fibrosis. In addition, it develops programs, including glucose-dependent insulinotropic polypeptide receptor (GIPR) program, which identified multiple GIPR agonist, dual GLP-1R/GIPR agonist, and GIPR antagonist hits for small molecule GIPR modulation that has the potential to provide a treatment in obesity; and GCG program, which identified multiple GCG receptor (GCGR) agonist and dual GLP-1R/GCGR agonist hits for small molecule GCGR modulation. The company was formerly known as ShouTi Inc. Structure Therapeutics Inc. was incorporated in 2016 and is headquartered in South San Francisco, California.

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All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.