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Design Therapeutics, Inc.

Stage 3 · Topping · week 4

As of Oct 22, 2026, Design Therapeutics is in Stage 3, the topping phase, now in week 4 (since Sep 25, 2026). It closed at $10.49, 34.2% below its 52-week high and below its 200-day average, which is rising.

Design Therapeutics, Inc. a clinical-stage biopharmaceutical company, research, designs, develops, and commercializes small molecule therapeutic drugs for the treatment of genetic diseases in the United States. More about the company

$10.49
-2.24% today
$656M · Small cap
Market Neutral — Building

Pro read

Pro

Our read

Topping: the uptrend is tiring

Setup score

—

Momentum

Steady

Edge

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Is DSGN early, or has it already run? Pro answers that for every US stock we cover, after every close.

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Stage Cycle Timeline2023-08-16 → 2026-10-22
S4 17w
S1 18w
S2 26w
S4 15w
S2 45w
2023-08-162026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S1 1w → S4 17w → S1 18w → S2 9w → S3 4w → S2 26w → S3 7w → S4 15w → S1 11w → S2 45w → S3 2w → S2 6w → S3 4w current
Total tracked: 165 weeks across 13 stage runs.

DSGN among Biotechnology59th of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…59DSGNStage 3 · wk 493−15.1%
vs 52W High
-34.2%
$5.53 lo$15.94 hi
34.2% below 52W high, weakening from peak
The stock is rolling over from its 52-week high. In Stage 3 distribution, new long positions carry high risk.
Stage Maturity
Week 4
1w13w26w
Week 4, early distribution
How long this stock has been in Stage 3 distribution. Longer tops often precede deeper Stage 4 declines.
vs 200 DMA
-13.5%
200 DMA: $12.13 · rising
Stock is losing its 200 DMA. Once lost, it confirms Stage 4 risk. This is a major red flag for existing holders.
Rel Volume
0.42x
vs 50-day avg
Volume spikes on down days during Stage 3 signal distribution, with institutions exiting. Stage analysis reads that as a warning against new long positions.
Trend Health
↓
Short-term trend rolling over
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
-15.1%
3M
-11.0%
6M
-17.9%
YTD
+15.3%
1Y
+86.3%
Scan Membership
Breakout Watch
Latest: 2024-07-29
3 appearances in last 60 days. First seen: 2022-08-03.
A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.
Recent Stage Timeline
2026-10-22S3
Wk 4 · Vol 0.42x
2026-10-21S3
Wk 4 · Vol 0.43x
2026-10-20S3
Wk 4 · Vol 0.90x
2026-10-19S3
Wk 4 · Vol 0.55x
2026-10-16S3
Wk 4 · Vol 1.34x
2026-10-15S3
Wk 3 · Vol 0.79x
2026-10-14S3
Wk 3 · Vol 1.69x
2026-10-13S3
Wk 3 · Vol 1.18x
2026-10-12S3
Wk 3 · Vol 0.49x
2026-10-09S3
Wk 3 · Vol 0.57x
2026-10-08S3
Wk 2 · Vol 1.08x
2026-10-07S3
Wk 2 · Vol 0.55x
Moving averages & range
50 DMA
$13.20
200 DMA
$12.13
52W High
$15.94
52W Low
$5.53
5D Low
$10.31
Resistance levels (recent highs)
20d High
$12.62
60d High
$15.94
120d High
$15.94
250d High
$15.94
Next resistance
+20.3%
to 20d High
ROE
-34.1%
Profit margin 0.0%
Dividend Yield
0.00%
P/B 3.3

Design Therapeutics: quick answers

What stage is Design Therapeutics in?

As of Oct 22, 2026, Design Therapeutics (DSGN) is in Stage 3, the topping phase. It entered Stage 3 on Sep 25, 2026 and is in week 4. What the four stages mean

Is Design Therapeutics in an uptrend?

Its uptrend has stalled. Design Therapeutics is in Stage 3, the topping phase that follows an advance. It trades 13.5% below its 200-day average, which is rising.

How far is Design Therapeutics from its 52-week high?

Design Therapeutics closed at $10.49 on Oct 22, 2026, 34.2% below its 52-week high of $15.94. Its 52-week low is $5.53.

How has Design Therapeutics performed over the past year?

As of Oct 22, 2026, Design Therapeutics is up 86.3% over the past year and up 15.3% so far in 2026.

Which sector and industry is Design Therapeutics in?

Design Therapeutics is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Design Therapeutics, Inc. a clinical-stage biopharmaceutical company, research, designs, develops, and commercializes small molecule therapeutic drugs for the treatment of genetic diseases in the United States. The company utilizes its GeneTAC platform to design and develop therapeutic candidates for inherited diseases caused by nucleotide repeat expansion. Its lead product candidates for potentially disease-modifying treatment comprises Friedreich Ataxia, a monogenic, autosomal recessive, progressive multi-system disease that affects organ systems dependent on mitochondrial function that brings to neurological, cardiac, and metabolic dysfunction; Myotonic Dystrophy Type-1, a dominantly-inherited, monogenic progressive neuromuscular disease affecting skeletal muscle, heart, brain, and other organs; Fuchs Endothelial Corneal Dystrophy, a genetic eye disease characterized by bilateral degeneration of corneal endothelial cells and progressive loss of vision; and Huntington's Disease, a dominantly inherited, monogenic neurodegenerative disease characterized by movement, cognitive, and psychiatric disorders. The company was incorporated in 2017 and is headquartered in Carlsbad, California.

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All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.