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Cue Biopharma, Inc.

Stage 3 · Topping · week 4

As of Oct 22, 2026, Cue Biopharma is in Stage 3, the topping phase, now in week 4 (since Oct 1, 2026). It closed at $18.89, 50.1% below its 52-week high and below its 200-day average, which is rising.

Cue Biopharma, Inc., a clinical-stage therapeutics company, focuses on developing various therapies for immunological disorders. More about the company

$18.89
-0.32% today
$137M · Micro cap
Market Neutral — Building

Pro read

Pro

Our read

Topping: the uptrend is tiring

Setup score

—

Momentum

Steady

Edge

—

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Stage Cycle Timeline2023-08-16 → 2026-10-22
S4 33w
S4 14w
S4 29w
S2 16w
2023-08-162026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S3 4w → S4 13w → S1 10w → S4 33w → S1 8w → S2 4w → S3 3w → S4 1w → S3 2w → S2 4w → S3 4w → S4 14w → S1 10w → S4 29w → S1 5w → S2 16w → S3 1w → S2 2w → S3 3w current
Total tracked: 164 weeks across 19 stage runs.

CUE among Biotechnology259th of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…259CUEStage 3 · wk 437−40.4%
vs 52W High
-50.1%
$5.31 lo$37.84 hi
50.1% below 52W high, weakening from peak
The stock is rolling over from its 52-week high. In Stage 3 distribution, new long positions carry high risk.
Stage Maturity
Week 4
1w13w26w
Week 4, early distribution
How long this stock has been in Stage 3 distribution. Longer tops often precede deeper Stage 4 declines.
vs 200 DMA
-9.5%
200 DMA: $20.88 · rising
Stock is losing its 200 DMA. Once lost, it confirms Stage 4 risk. This is a major red flag for existing holders.
Rel Volume
0.19x
vs 50-day avg
Volume spikes on down days during Stage 3 signal distribution, with institutions exiting. Stage analysis reads that as a warning against new long positions.
Trend Health
↓
Short-term trend rolling over
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
-40.4%
3M
-41.2%
6M
+13.7%
YTD
+86.8%
1Y
-23.7%
Scan Membership
Breakout Watch
Latest: 2025-02-18
10 appearances in last 60 days. First seen: 2019-04-18.
A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.
Recent Stage Timeline
2026-10-22S3
Wk 4 · Vol 0.19x
2026-10-21S3
Wk 3 · Vol 0.34x
2026-10-20S3
Wk 3 · Vol 0.56x
2026-10-19S3
Wk 3 · Vol 0.45x
2026-10-16S3
Wk 3 · Vol 0.36x
2026-10-15S3
Wk 3 · Vol 0.77x
2026-10-14S3
Wk 2 · Vol 0.83x
2026-10-13S3
Wk 2 · Vol 1.03x
2026-10-12S3
Wk 2 · Vol 0.60x
2026-10-09S3
Wk 2 · Vol 1.33x
2026-10-08S3
Wk 2 · Vol 0.37x
2026-10-07S3
Wk 1 · Vol 0.45x
Moving averages & range
50 DMA
$26.54
200 DMA
$20.88
52W High
$37.84
52W Low
$5.31
5D Low
$16.08
Resistance levels (recent highs)
20d High
$31.41
60d High
$37.84
120d High
$37.84
250d High
$37.84
Next resistance
+66.3%
to 20d High
ROE
-1603.5%
Profit margin 0.0%
Dividend Yield
0.00%
P/B 42.7

Cue Biopharma: quick answers

What stage is Cue Biopharma in?

As of Oct 22, 2026, Cue Biopharma (CUE) is in Stage 3, the topping phase. It entered Stage 3 on Oct 1, 2026 and is in week 4. What the four stages mean

Is Cue Biopharma in an uptrend?

Its uptrend has stalled. Cue Biopharma is in Stage 3, the topping phase that follows an advance. It trades 9.5% below its 200-day average, which is rising.

How far is Cue Biopharma from its 52-week high?

Cue Biopharma closed at $18.89 on Oct 22, 2026, 50.1% below its 52-week high of $37.84. Its 52-week low is $5.31.

How has Cue Biopharma performed over the past year?

As of Oct 22, 2026, Cue Biopharma is down 23.7% over the past year and up 86.8% so far in 2026.

Which sector and industry is Cue Biopharma in?

Cue Biopharma is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Cue Biopharma, Inc., a clinical-stage therapeutics company, focuses on developing various therapies for immunological disorders. The company's lead asset is CUE-221, an anti-IgE antibody with a dual-mechanism of action currently in Phase 2 development for allergic diseases. It also developed the Immuno-STAT platform, which targets disease-specific T cells in vivo without broad immune modulation. The company's lead autoimmune candidate is CUE-401, a bifunctional IL-2 and TGF-B program that is advancing towards Phase 1 development to regulate inflammation and drive Treg-mediated tolerance. The company was formerly known as Imagen Biopharma, Inc. and changed its name to Cue Biopharma, Inc. in October 2016. Cue Biopharma, Inc. was incorporated in 2014 and is headquartered in Boston, Massachusetts.

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All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.