Xenetic Biosciences, Inc.

Stage 3 · Topping · week 3

As of Oct 22, 2026, Xenetic Biosciences is in Stage 3, the topping phase, now in week 3 (since Oct 8, 2026). It closed at $1.93, 58.7% below its 52-week high and below its 200-day average, which is falling.

Xenetic Biosciences, Inc., a biopharmaceutical company, focuses on advancing immune-oncology technologies to treat cancers. More about the company

$1.93

-4.46% today

$4.5M · Micro cap

Market Neutral — Building

Pro read

Pro

Our read

Topping: the uptrend is tiring

Setup score

—

Momentum

Steady

Edge

—

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Stage Cycle Timeline2023-08-16 → 2026-10-22

S4 14w

2023-08-162026-10-22

S1S2S3S4Setup score (0–10, dashed line at 5)

S1 5w → S2 5w → S3 2w → S4 10w → S1 7w → S2 10w → S3 8w → S2 4w → S3 5w → S4 4w → S1 6w → S2 1w → S1 2w → S2 9w → S3 3w → S4 14w → S1 8w → S4 6w → S1 1w → S2 6w → S3 4w → S4 12w → S1 8w → S2 8w → S3 8w → S2 6w → S3 2w current

Total tracked: 165 weeks across 27 stage runs.

XBIO among Biotechnology352nd of 591 by relative strength

All 591 →

Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#	Stock	Stage	RS	1M
1	GTBPGT Biopharma, Inc.	Stage 2 · wk 7	99	−22.3%
2	IOVAIovance Biotherapeutics, Inc.	Stage 2 · wk 18	99	+38.8%
3	SLSSELLAS Life Sciences Group, Inc.	Stage 3 · wk 4	99	−1.5%
4	MRNAModerna, Inc.	Stage 2 · wk 17	99	+11.3%
5	TWSTTwist Bioscience Corporation	Stage 2 · wk 39	99	−14.5%
6	KODKodiak Sciences Inc	Stage 2 · wk 4	99	+172.1%
7	ERASErasca, Inc.	Stage 3 · wk 5	99	+0.7%
8	CLYMClimb Bio, Inc.	Stage 3 · wk 3	99	−15.8%
…352	XBIOXenetic Biosciences, Inc.	Stage 3 · wk 3	23	−23.4%

vs 52W High

-58.7%

$1.93 lo$4.67 hi

58.7% below 52W high, weakening from peak

The stock is rolling over from its 52-week high. In Stage 3 distribution, new long positions carry high risk.

Stage Maturity

Week 3

1w13w26w

Week 3, early distribution

How long this stock has been in Stage 3 distribution. Longer tops often precede deeper Stage 4 declines.

vs 200 DMA

-32.3%

200 DMA: $2.85 · sloping down

Stock is losing its 200 DMA. Once lost, it confirms Stage 4 risk. This is a major red flag for existing holders.

Rel Volume

0.22x

vs 50-day avg

Volume spikes on down days during Stage 3 signal distribution, with institutions exiting. Stage analysis reads that as a warning against new long positions.

Trend Health

↓

Short-term trend rolling over

Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.

-23.4%

-26.9%

-38.3%

YTD

-10.2%

-50.1%

Scan Membership

Breakout Watch

Latest: 2024-12-24

9 appearances in last 60 days. First seen: 2018-12-13.

A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.

Recent Stage Timeline

2026-10-22S3

Wk 3 · Vol 0.22x

2026-10-21S3

Wk 2 · Vol 0.08x

2026-10-20S3

Wk 2 · Vol 0.13x

2026-10-19S3

Wk 2 · Vol 0.10x

2026-10-16S3

Wk 2 · Vol 0.17x

2026-10-15S3

Wk 2 · Vol 0.49x

2026-10-14S3

Wk 1 · Vol 0.12x

2026-10-13S3

Wk 1 · Vol 0.32x

2026-10-12S3

Wk 1 · Vol 0.08x

2026-10-09S3

Wk 1 · Vol 0.10x

2026-10-08S32→3

Wk 1 · Vol 0.13x

2026-10-07S2

Wk 6 · Vol 0.15x

Moving averages & range

50 DMA

$3.01

200 DMA

$2.85

52W High

$4.67

52W Low

$1.93

5D Low

$1.93

Resistance levels (recent highs)

20d High

$2.39

60d High

$4.67

120d High

$4.67

250d High

$4.67

Next resistance

+23.8%

to 20d High

ROE

-47.0%

Profit margin -75.9%

Dividend Yield

0.00%

P/B 0.7

Xenetic Biosciences: quick answers

What stage is Xenetic Biosciences in?

As of Oct 22, 2026, Xenetic Biosciences (XBIO) is in Stage 3, the topping phase. It entered Stage 3 on Oct 8, 2026 and is in week 3. What the four stages mean

Is Xenetic Biosciences in an uptrend?

Its uptrend has stalled. Xenetic Biosciences is in Stage 3, the topping phase that follows an advance. It trades 32.3% below its 200-day average, which is falling.

How far is Xenetic Biosciences from its 52-week high?

Xenetic Biosciences closed at $1.93 on Oct 22, 2026, 58.7% below its 52-week high of $4.67. Its 52-week low is $1.93.

How has Xenetic Biosciences performed over the past year?

As of Oct 22, 2026, Xenetic Biosciences is down 50.1% over the past year and down 10.2% so far in 2026.

Which sector and industry is Xenetic Biosciences in?

Xenetic Biosciences is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Xenetic Biosciences, Inc., a biopharmaceutical company, focuses on advancing immune-oncology technologies to treat cancers. Its DNase technology targets neutrophil extracellular traps (NETS), which are involved in cancer growth, metastasis, and progression, and contribute to immunotherapy, chemotherapy, and radiotherapy resistance. The company's product pipeline includes XBIO-015 for the treatment of pancreatic carcinoma and solid tumors; XBIO-020 for the treatment of solid tumors; and ErepoXen, which uses PolyXen platform technology for the treatment of anemia in chronic kidney disease (CKD) patients. It has a sublicensing agreement with Takeda Pharmaceutical Co. Ltd, as well as various research, development, license and supply agreements with Serum Institute of India, PJSC Pharmsynthez, and SynBio, LLC. Xenetic Biosciences, Inc. is headquartered in Framingham, Massachusetts.

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All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.