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Senti Biosciences Holdings, Inc.

Stage 4 · Declining · week 14

As of Oct 22, 2026, Senti Biosciences Holdings is in Stage 4, the downtrend phase, now in week 14 (since Jul 17, 2026). It closed at $0.19, 92.0% below its 52-week high and below its 200-day average, which is falling.

Senti Biosciences Holdings, Inc., a clinical stage biotechnology company, develops cell and gene therapies engineered with its gene circuit platform technologies for patients living with incurable diseases. More about the company

$0.19
-10.87% today
$5.9M · Micro cap
Market Neutral — Building

Pro read

Pro

Our read

Declining, below its long-term trend

Setup score

—

Momentum

Steady

Edge

—

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Stage Cycle Timeline2023-08-16 → 2026-10-22
S4 19w
S4 32w
S3 14w
S4 19w
S4 17w
S4 14w
2023-08-162026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S4 19w → S1 10w → S4 32w → S1 2w → S4 3w → S1 1w → S2 11w → S3 14w → S4 19w → S1 9w → S4 17w → S1 11w → S4 14w current
Total tracked: 165 weeks across 13 stage runs.

SNTI among Biotechnology513th of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…513SNTIStage 4 · wk 147−43.5%
vs 52W High
-92.0%
$0.19 lo$2.39 hi
92.0% below 52W high, deep Stage 4 damage
In Stage 4, distance from the 52-week high reflects an ongoing decline, not a discount.
Stage Maturity
Week 14
1w13w26w
Week 14, established downtrend
How long this stock has been in Stage 4 decline. The longer the downtrend, the more entrenched the selling pressure. No length of decline marks a bottom on its own.
vs 200 DMA
-74.6%
200 DMA: $0.75 · sloping down
In Stage 4, the stock is below its 200-day average, the hallmark of a downtrend. Stage analysis waits for that to reverse before buying.
Rel Volume
0.19x
vs 50-day avg
High volume on down days in Stage 4 confirms institutional selling. Low-volume bounces are typical. They lack real buyers and are easy to mistake for reversals.
Trend Health
↓
Short-term trend rolling over
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
-43.5%
3M
-52.7%
6M
-81.1%
YTD
-82.6%
1Y
-90.7%
Scan Membership
Breakout Watch
Latest: 2024-12-16
A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.
Recent Stage Timeline
2026-10-22S4
Wk 14 · Vol 0.19x
2026-10-21S4
Wk 14 · Vol 0.24x
2026-10-20S4
Wk 14 · Vol 0.28x
2026-10-19S4
Wk 14 · Vol 0.29x
2026-10-16S4
Wk 13 · Vol 3.58x
2026-10-15S4
Wk 13 · Vol 31.73x
2026-10-14S4
Wk 13 · Vol 0.28x
2026-10-13S4
Wk 13 · Vol 0.51x
2026-10-12S4
Wk 13 · Vol 0.24x
2026-10-09S4
Wk 12 · Vol 0.18x
2026-10-08S4
Wk 12 · Vol 0.42x
2026-10-07S4
Wk 12 · Vol 0.56x
Moving averages & range
50 DMA
$0.33
200 DMA
$0.75
52W High
$2.39
52W Low
$0.19
5D Low
$0.19
Resistance levels (recent highs)
20d High
$0.35
60d High
$0.46
120d High
$1.11
250d High
$2.39
Next resistance
+80.6%
to 20d High
ROE
-466.5%
Profit margin 0.0%
Dividend Yield
0.00%
P/B -1.7

Senti Biosciences Holdings: quick answers

What stage is Senti Biosciences Holdings in?

As of Oct 22, 2026, Senti Biosciences Holdings (SNTI) is in Stage 4, the downtrend phase. It entered Stage 4 on Jul 17, 2026 and is in week 14. What the four stages mean

Is Senti Biosciences Holdings in an uptrend?

No. Senti Biosciences Holdings is in a Stage 4 downtrend. It trades 74.6% below its 200-day average, which is falling.

How far is Senti Biosciences Holdings from its 52-week high?

Senti Biosciences Holdings closed at $0.19 on Oct 22, 2026, 92.0% below its 52-week high of $2.39. Its 52-week low is $0.19.

How has Senti Biosciences Holdings performed over the past year?

As of Oct 22, 2026, Senti Biosciences Holdings is down 90.7% over the past year and down 82.6% so far in 2026.

Which sector and industry is Senti Biosciences Holdings in?

Senti Biosciences Holdings is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Senti Biosciences Holdings, Inc., a clinical stage biotechnology company, develops cell and gene therapies engineered with its gene circuit platform technologies for patients living with incurable diseases. The company's lead product candidates utilize off-the-shelf healthy adult donor derived natural killer (NK) cells to create CAR-NK cells outfitted with gene circuit technologies in various oncology indications with unmet need. It offers SENTI-202, a logic gated off-the-shelf CAR-NK cell therapy for the treatment of blood cancers and relapsed/refractory hematological malignancies, including acute myeloid leukemia. In addition, the company develops the tumor-associated antigen and protective antigen paired discovery platform to select and validate NOT GATE antigen candidates and identify tumor-associated antigens in cancer cells. Further, its pipeline includes preclinical programs, which comprise a solid tumor cell therapy program; and partnered programs related to cell therapies for regenerative medicines. The company has a strategic collaboration with Celest Therapeutics (Shanghai) Co. Ltd. The company was formerly known as Senti Biosciences, Inc. and changed its name to Senti Biosciences Holdings, Inc. in April 2026. The company was incorporated in 2016 and is headquartered in South San Francisco, California.

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All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.