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Protagonist Therapeutics, Inc.

Stage 2 · Advancing · week 31

As of Oct 22, 2026, Protagonist Therapeutics is in Stage 2, the uptrend phase, now in week 31 (since Mar 16, 2026). It closed at $139.53, 12.0% below its 52-week high and above its 200-day average, which is rising.

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. More about the company

$139.53
+0.38% today
$9.0B · Mid cap
Market Neutral — Building

Pro read

Pro

Our read

In Stage 2, but it has already run

Setup score

—

Momentum

Steady

Edge

—

Setup-score rank among Stage 2 peers: #1 of 110 in Biotechnology · #1 of 272 in Health Care

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Loading price chart…
Stage Cycle Timeline2023-08-16 → 2026-10-22
S2 14w
S2 26w
S2 34w
S2 32w
2023-08-162026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S3 5w → S4 12w → S1 6w → S2 14w → S3 4w → S2 26w → S3 10w → S4 4w → S1 1w → S2 11w → S3 2w → S2 34w → S3 4w → S2 32w current
Total tracked: 166 weeks across 14 stage runs.

PTGX among Biotechnology58th of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…58PTGXStage 2 · wk 3193+0.6%
vs 52W High
-12.0%
$73.50 lo$158.62 hi
12.0% below 52W high, pullback range
How far this stock is from its 52-week high. A pullback of 3–20% while Stage 2 structure holds is typically a better entry than chasing near the high.
Stage Maturity
Week 31
1w13w26w
Week 31, mature
How long this stock has been in Stage 2. The sweet spot is mid-run: long enough to prove the structure holds, not so long that it's extended. Very fresh moves (weeks 1–4) often need more time to confirm.
vs 200 DMA
21.5%
200 DMA: $114.82 · rising
Long-term trend anchor. When the stock and the S&P 500 are both above their 200-day averages, the backdrop supports continuation.
Rel Volume
0.60x
vs 50-day avg
Low vol (0.5–1x) on pullbacks = resting, not being sold. High vol on breakouts = commitment. Volume spike on down days is a warning sign.
Trend Health
↓
Short-term trend rolling over
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
+0.6%
3M
+2.5%
6M
+36.0%
YTD
+60.0%
1Y
+86.0%
Scan Membership
Breakout Watch
Latest: 2025-06-20
9 appearances in last 60 days. First seen: 2019-03-18.
A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.
Recent Stage Timeline
2026-10-22S2
Wk 31 · Vol 0.60x
2026-10-21S2
Wk 31 · Vol 0.83x
2026-10-20S2
Wk 31 · Vol 1.16x
2026-10-19S2
Wk 31 · Vol 0.99x
2026-10-16S2
Wk 30 · Vol 1.34x
2026-10-15S2
Wk 30 · Vol 1.08x
2026-10-14S2
Wk 30 · Vol 1.04x
2026-10-13S2
Wk 30 · Vol 1.61x
2026-10-12S2
Wk 30 · Vol 1.42x
2026-10-09S2
Wk 29 · Vol 1.21x
2026-10-08S2
Wk 29 · Vol 1.61x
2026-10-07S2
Wk 29 · Vol 1.52x
Moving averages & range
50 DMA
$144.49
200 DMA
$114.82
52W High
$158.62
52W Low
$73.50
5D Low
$128.75
Resistance levels (recent highs)
20d High
$144.88
60d High
$158.62
120d High
$158.62
250d High
$158.62
Next resistance
+3.8%
to 20d High
P/E (TTM)
135.5
Forward -1405.7
ROE
+11.0%
Profit margin +29.4%
Dividend Yield
0.00%
P/B 10.7

Protagonist Therapeutics: quick answers

What stage is Protagonist Therapeutics in?

As of Oct 22, 2026, Protagonist Therapeutics (PTGX) is in Stage 2, the uptrend phase. It entered Stage 2 on Mar 16, 2026 and is in week 31. What the four stages mean

Is Protagonist Therapeutics in an uptrend?

Yes. Protagonist Therapeutics is in a Stage 2 uptrend. It trades 21.5% above its 200-day average, which is rising.

How far is Protagonist Therapeutics from its 52-week high?

Protagonist Therapeutics closed at $139.53 on Oct 22, 2026, 12.0% below its 52-week high of $158.62. Its 52-week low is $73.50.

How has Protagonist Therapeutics performed over the past year?

As of Oct 22, 2026, Protagonist Therapeutics is up 86.0% over the past year and up 60.0% so far in 2026.

Which sector and industry is Protagonist Therapeutics in?

Protagonist Therapeutics is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is also developing PN-881, a potential best-in-class oral peptide IL-17 antagonist, for the treatment of immune-mediated skin diseases in Phase 1 clinical trials; PN-477 and PN-458, which are development candidates for the treatment of obesity; PN-8047, an orally administered hepcidin functional mimetic small molecule; L-4R alpha antagonist for the treatment of atopic dermatitis and moderate-to-severe asthma; and amylinR-based oral and subcutaneous mono- and poly-agonists for the treatment of obesity. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.

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All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.