Skip to main content
Indian stocks: Visit www.stage2stocks.com →

Puma Biotechnology Inc

Stage 2 · Advancing · week 69

As of Oct 22, 2026, Puma Biotechnology is in Stage 2, the uptrend phase, now in week 69 (since Jun 11, 2025). It closed at $11.26, at its 52-week high and above its 200-day average, which is rising.

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. More about the company

$11.26
+3.30% today
$581M · Small cap
Market Neutral — Fading

Pro read

Pro

Our read

In Stage 2, but it has already run

Setup score

—

Momentum

Steady

Edge

—

Setup-score rank among Stage 2 peers: #1 of 110 in Biotechnology · #1 of 272 in Health Care

Is PBYI early, or has it already run? Pro answers that for every US stock we cover, after every close.

Get Pro · $19 a month

Renews monthly until you cancel. Cancel any time in Plan & billing.

Loading price chart…
Stage Cycle Timeline2023-08-16 → 2026-10-22
S2 19w
S4 20w
S2 71w
2023-08-162026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S1 5w → S4 10w → S1 2w → S2 19w → S3 8w → S4 20w → S1 13w → S4 3w → S2 5w → S3 2w → S2 4w → S3 2w → S2 71w current
Total tracked: 166 weeks across 13 stage runs.

PBYI among Biotechnology34th of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…34PBYIStage 2 · wk 6996+21.3%
vs 52W High
0.0%
$4.73 lo$11.26 hi
Near 52W high
How far this stock is from its 52-week high. A pullback of 3–20% while Stage 2 structure holds is typically a better entry than chasing near the high.
Stage Maturity
Week 69
1w13w26w
Week 69, extended Stage 2
How long this stock has been in Stage 2. The sweet spot is mid-run: long enough to prove the structure holds, not so long that it's extended. Very fresh moves (weeks 1–4) often need more time to confirm.
vs 200 DMA
44.8%
200 DMA: $7.78 · rising
Long-term trend anchor. When the stock and the S&P 500 are both above their 200-day averages, the backdrop supports continuation.
Rel Volume
1.25x
vs 50-day avg
Low vol (0.5–1x) on pullbacks = resting, not being sold. High vol on breakouts = commitment. Volume spike on down days is a warning sign.
Trend Health
↑
Short-term trend rising strongly
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
+21.3%
3M
+41.1%
6M
+52.2%
YTD
+95.1%
1Y
+117.8%
Scan Membership
Breakout Watch
Latest: 2025-03-10
8 appearances in last 60 days. First seen: 2019-04-30.
A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.
Recent Stage Timeline
2026-10-22S2
Wk 69 · Vol 1.25x
2026-10-21S2
Wk 69 · Vol 0.81x
2026-10-20S2
Wk 69 · Vol 1.14x
2026-10-19S2
Wk 69 · Vol 1.42x
2026-10-16S2
Wk 68 · Vol 1.24x
2026-10-15S2
Wk 68 · Vol 1.16x
2026-10-14S2
Wk 68 · Vol 1.01x
2026-10-13S2
Wk 68 · Vol 0.91x
2026-10-12S2
Wk 68 · Vol 0.88x
2026-10-09S2
Wk 67 · Vol 0.94x
2026-10-08S2
Wk 67 · Vol 1.12x
2026-10-07S2
Wk 67 · Vol 1.18x
Moving averages & range
50 DMA
$9.61
200 DMA
$7.78
52W High
$11.26
52W Low
$4.73
5D Low
$9.83
Resistance levels (recent highs)
20d High
$11.26
60d High
$11.26
120d High
$11.26
250d High
$11.26
Next resistance
Above all
P/E (TTM)
22.1
Forward 32.2
Earnings Growth (YoY)
+35.8%
Revenue +7.8%
ROE
+22.0%
Profit margin +11.6%
Dividend Yield
0.00%
P/B 4.2

Puma Biotechnology: quick answers

What stage is Puma Biotechnology in?

As of Oct 22, 2026, Puma Biotechnology (PBYI) is in Stage 2, the uptrend phase. It entered Stage 2 on Jun 11, 2025 and is in week 69. What the four stages mean

Is Puma Biotechnology in an uptrend?

Yes. Puma Biotechnology is in a Stage 2 uptrend. It trades 44.8% above its 200-day average, which is rising.

How far is Puma Biotechnology from its 52-week high?

Puma Biotechnology closed at $11.26 on Oct 22, 2026, at its 52-week high. Its 52-week low is $4.73.

How has Puma Biotechnology performed over the past year?

As of Oct 22, 2026, Puma Biotechnology is up 117.8% over the past year and up 95.1% so far in 2026.

Which sector and industry is Puma Biotechnology in?

Puma Biotechnology is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. It offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. The company also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breast cancer, triple negative breast cancer, small cell lung cancer, and head and neck cancer. It sells its products through specialty pharmacy and distributor networks. The company has license agreements with Pfizer Inc. for the development, manufacture, and commercialization of neratinib (oral), neratinib (intravenous), PB357, and related compounds, as well as sub-license agreements with Specialised Therapeutics Asia Pte Ltd., Medison Pharma Ltd., Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. Puma Biotechnology, Inc. was founded in 2010 and is headquartered in Los Angeles, California.

Visit company website →

All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.