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MacroGenics, Inc.

Stage 3 · Topping · week 10

As of Oct 22, 2026, MacroGenics is in Stage 3, the topping phase, now in week 10 (since Aug 18, 2026). It closed at $3.63, 25.3% below its 52-week high and above its 200-day average, which is rising.

MacroGenics, Inc., a clinical-stage biopharmaceutical company, discovers, develops, manufactures, and commercializes antibody-based therapeutics for the treatment of cancer in the United States. More about the company

$3.63
+1.11% today
$231M · Micro cap
Market Neutral — Building

Pro read

Pro

Our read

Topping: the uptrend is tiring

Setup score

—

Momentum

Steady

Edge

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Stage Cycle Timeline2023-08-16 → 2026-10-22
S2 22w
S4 20w
S4 26w
S1 14w
S2 29w
2023-08-162026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S4 12w → S1 3w → S2 22w → S3 6w → S4 20w → S1 7w → S4 26w → S1 3w → S4 3w → S1 14w → S4 10w → S1 1w → S2 29w → S3 9w current
Total tracked: 165 weeks across 14 stage runs.

MGNX among Biotechnology62nd of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…62MGNXStage 3 · wk 1092−4.5%
vs 52W High
-25.3%
$1.33 lo$4.86 hi
25.3% below 52W high, weakening from peak
The stock is rolling over from its 52-week high. In Stage 3 distribution, new long positions carry high risk.
Stage Maturity
Week 10
1w13w26w
Week 10, distribution
How long this stock has been in Stage 3 distribution. Longer tops often precede deeper Stage 4 declines.
vs 200 DMA
6.7%
200 DMA: $3.40 · rising
Stock is losing its 200 DMA. Once lost, it confirms Stage 4 risk. This is a major red flag for existing holders.
Rel Volume
0.85x
vs 50-day avg
Volume spikes on down days during Stage 3 signal distribution, with institutions exiting. Stage analysis reads that as a warning against new long positions.
Trend Health
↓
Short-term trend rolling over
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
-4.5%
3M
-1.9%
6M
+14.2%
YTD
+125.5%
1Y
+79.7%
Scan Membership
Breakout Watch
Latest: 2023-12-04
6 appearances in last 60 days. First seen: 2019-04-04.
A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.
Recent Stage Timeline
2026-10-22S3
Wk 10 · Vol 0.85x
2026-10-21S3
Wk 10 · Vol 0.63x
2026-10-20S3
Wk 9 · Vol 0.59x
2026-10-19S3
Wk 9 · Vol 1.04x
2026-10-16S3
Wk 9 · Vol 0.74x
2026-10-15S3
Wk 9 · Vol 1.06x
2026-10-14S3
Wk 9 · Vol 1.66x
2026-10-13S3
Wk 8 · Vol 1.02x
2026-10-12S3
Wk 8 · Vol 0.52x
2026-10-09S3
Wk 8 · Vol 0.77x
2026-10-08S3
Wk 8 · Vol 1.43x
2026-10-07S3
Wk 8 · Vol 0.94x
Moving averages & range
50 DMA
$3.90
200 DMA
$3.40
52W High
$4.86
52W Low
$1.33
5D Low
$3.25
Resistance levels (recent highs)
20d High
$4.06
60d High
$4.40
120d High
$4.86
250d High
$4.86
Next resistance
+11.8%
to 20d High
ROE
-225.8%
Profit margin -8.3%
Dividend Yield
0.00%
P/B 5.4

MacroGenics: quick answers

What stage is MacroGenics in?

As of Oct 22, 2026, MacroGenics (MGNX) is in Stage 3, the topping phase. It entered Stage 3 on Aug 18, 2026 and is in week 10. What the four stages mean

Is MacroGenics in an uptrend?

Its uptrend has stalled. MacroGenics is in Stage 3, the topping phase that follows an advance. It trades 6.7% above its 200-day average, which is rising.

How far is MacroGenics from its 52-week high?

MacroGenics closed at $3.63 on Oct 22, 2026, 25.3% below its 52-week high of $4.86. Its 52-week low is $1.33.

How has MacroGenics performed over the past year?

As of Oct 22, 2026, MacroGenics is up 79.7% over the past year and up 125.5% so far in 2026.

Which sector and industry is MacroGenics in?

MacroGenics is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

MacroGenics, Inc., a clinical-stage biopharmaceutical company, discovers, develops, manufactures, and commercializes antibody-based therapeutics for the treatment of cancer in the United States. The company's product pipeline includes lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4 for the treatment of mCRPC and docetaxel that is in phase 2 clinical trials, as well as for the treatment of platinum-resistant ovarian cancer and clear cell gynecologic cancer which has completed phase 1 clinical trial; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload; MGC028, an antibody-drug conjugates (ADC) that targets ADAM9 and delivers a novel TOP1i-based linker-payload for the treatment of solid tumors, which is in phase 1 clinical trials; MGC030, a ADC molecule that targets an undisclosed antigen expressed across several solid tumors, which is in preclinical trials. It is also developing T-cell engager programs. The company has collaborations with TerSera Therapeutics LLC; Incyte Corporation; and Gilead Sciences, Inc. MacroGenics, Inc. was incorporated in 2000 and is headquartered in Rockville, Maryland.

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All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.