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Maze Therapeutics, Inc.

Stage 4 · Declining · week 6

As of Oct 22, 2026, Maze Therapeutics is in Stage 4, the downtrend phase, now in week 6 (since Sep 17, 2026). It closed at $31.95, 38.4% below its 52-week high and below its 200-day average, which is falling.

Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States. More about the company

$31.95
-1.93% today
$1.8B · Small cap
Market Neutral — Building

Pro read

Pro

Our read

Declining, below its long-term trend

Setup score

—

Momentum

Accelerating ⇈

Edge

—

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Loading price chart…
Stage Cycle Timeline2025-01-31 → 2026-10-22
S? 41w
S2 21w
S4 7w
S1 10w
2025-01-312026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S? 41w → S2 21w → S3 6w → S4 7w → S1 10w → S4 5w current
Total tracked: 90 weeks across 6 stage runs.

MAZE among Biotechnology158th of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…158MAZEStage 4 · wk 661+13.7%
vs 52W High
-38.4%
$22.39 lo$51.84 hi
38.4% below 52W high, deep Stage 4 damage
In Stage 4, distance from the 52-week high reflects an ongoing decline, not a discount.
Stage Maturity
Week 6
1w13w26w
Week 6, early Stage 4 decline
How long this stock has been in Stage 4 decline. The longer the downtrend, the more entrenched the selling pressure. No length of decline marks a bottom on its own.
vs 200 DMA
-0.5%
200 DMA: $32.12 · sloping down
In Stage 4, the stock is below its 200-day average, the hallmark of a downtrend. Stage analysis waits for that to reverse before buying.
Rel Volume
1.23x
vs 50-day avg
High volume on down days in Stage 4 confirms institutional selling. Low-volume bounces are typical. They lack real buyers and are easy to mistake for reversals.
Trend Health
↑ ⇈
Short-term trend rising strongly, and accelerating
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
+13.7%
3M
+15.4%
6M
+22.8%
YTD
-19.7%
1Y
+8.2%
Scan Membership
Not in any current scan.
Recent Stage Timeline
2026-10-22S4
Wk 6 · Vol 1.23x
2026-10-21S4
Wk 5 · Vol 1.50x
2026-10-20S4
Wk 5 · Vol 2.27x
2026-10-19S4
Wk 5 · Vol 1.92x
2026-10-16S4
Wk 5 · Vol 1.55x
2026-10-15S4
Wk 5 · Vol 0.83x
2026-10-14S4
Wk 4 · Vol 1.30x
2026-10-13S4
Wk 4 · Vol 0.96x
2026-10-12S4
Wk 4 · Vol 2.34x
2026-10-09S4
Wk 4 · Vol 1.10x
2026-10-08S4
Wk 4 · Vol 1.51x
2026-10-07S4
Wk 3 · Vol 1.40x
Moving averages & range
50 DMA
$27.13
200 DMA
$32.12
52W High
$51.84
52W Low
$22.39
5D Low
$27.53
Resistance levels (recent highs)
20d High
$32.58
60d High
$32.58
120d High
$32.84
250d High
$51.84
Next resistance
+2.0%
to 20d High
ROE
-37.3%
Profit margin 0.0%
Dividend Yield
0.00%
P/B 3.9

Maze Therapeutics: quick answers

What stage is Maze Therapeutics in?

As of Oct 22, 2026, Maze Therapeutics (MAZE) is in Stage 4, the downtrend phase. It entered Stage 4 on Sep 17, 2026 and is in week 6. What the four stages mean

Is Maze Therapeutics in an uptrend?

No. Maze Therapeutics is in a Stage 4 downtrend. It trades 0.5% below its 200-day average, which is falling.

How far is Maze Therapeutics from its 52-week high?

Maze Therapeutics closed at $31.95 on Oct 22, 2026, 38.4% below its 52-week high of $51.84. Its 52-week low is $22.39.

How has Maze Therapeutics performed over the past year?

As of Oct 22, 2026, Maze Therapeutics is up 8.2% over the past year and down 19.7% so far in 2026.

Which sector and industry is Maze Therapeutics in?

Maze Therapeutics is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States. Its lead programs include MZE829, an oral small molecule inhibitor of apolipoprotein L1, or APOL1, which is in phase II clinical trial for the treatment of patients with APOL1 kidney disease; and MZE782, an oral small molecule inhibitor that is in phase II ready clinical trial for the treatment of phenylketonuria and chronic kidney disease. The company also develops MZE001, an investigational oral small molecule inhibitor of muscle-specific glycogen synthase clinical program for the treatment of Pompe disease. It has a license agreement with Trace Neuroscience, Inc. to discovery research program targets UNC13A; the Shionogi & Co., Ltd to research, develop, manufacture, and commercialize MZE001; and Neurocrine Biosciences, Inc. to discover research program that targets ATXN2. The company was formerly known as Modulus Therapeutics, Inc. and changed its name to Maze Therapeutics, Inc. in September 2018. The company was incorporated in 2017 and is based in South San Francisco, California.

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All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.