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Lexicon Pharmaceuticals, Inc.

Stage 3 · Topping · week 5

As of Oct 22, 2026, Lexicon Pharmaceuticals is in Stage 3, the topping phase, now in week 5 (since Sep 21, 2026). It closed at $1.49, 43.6% below its 52-week high and below its 200-day average, which is rising.

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. More about the company

$1.49
-5.70% today
$663M · Small cap
Market Neutral — Building

Pro read

Pro

Our read

Topping: the uptrend is tiring

Setup score

—

Momentum

Steady

Edge

—

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Loading price chart…
Stage Cycle Timeline2023-08-16 → 2026-10-22
S4 18w
S4 26w
S2 21w
S2 29w
2023-08-162026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S4 18w → S1 9w → S2 9w → S3 12w → S2 6w → S3 1w → S4 9w → S1 1w → S4 26w → S1 10w → S2 21w → S3 10w → S2 29w → S3 5w current
Total tracked: 166 weeks across 14 stage runs.

LXRX among Biotechnology176th of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…176LXRXStage 3 · wk 557−27.7%
vs 52W High
-43.6%
$1.14 lo$2.64 hi
43.6% below 52W high, weakening from peak
The stock is rolling over from its 52-week high. In Stage 3 distribution, new long positions carry high risk.
Stage Maturity
Week 5
1w13w26w
Week 5, early distribution
How long this stock has been in Stage 3 distribution. Longer tops often precede deeper Stage 4 declines.
vs 200 DMA
-20.6%
200 DMA: $1.88 · rising
Stock is losing its 200 DMA. Once lost, it confirms Stage 4 risk. This is a major red flag for existing holders.
Rel Volume
0.49x
vs 50-day avg
Volume spikes on down days during Stage 3 signal distribution, with institutions exiting. Stage analysis reads that as a warning against new long positions.
Trend Health
↓
Short-term trend rolling over
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
-27.7%
3M
-34.9%
6M
-11.3%
YTD
+30.7%
1Y
+3.5%
Scan Membership
Breakout Watch
Latest: 2024-07-17
6 appearances in last 60 days. First seen: 2020-12-24.
A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.
Recent Stage Timeline
2026-10-22S3
Wk 5 · Vol 0.49x
2026-10-21S3
Wk 5 · Vol 0.45x
2026-10-20S3
Wk 5 · Vol 0.51x
2026-10-19S3
Wk 5 · Vol 0.61x
2026-10-16S3
Wk 4 · Vol 0.70x
2026-10-15S3
Wk 4 · Vol 0.49x
2026-10-14S3
Wk 4 · Vol 0.64x
2026-10-13S3
Wk 4 · Vol 0.69x
2026-10-12S3
Wk 4 · Vol 0.68x
2026-10-09S3
Wk 3 · Vol 0.69x
2026-10-08S3
Wk 3 · Vol 1.12x
2026-10-07S3
Wk 3 · Vol 0.37x
Moving averages & range
50 DMA
$1.99
200 DMA
$1.88
52W High
$2.64
52W Low
$1.14
5D Low
$1.49
Resistance levels (recent highs)
20d High
$1.90
60d High
$2.49
120d High
$2.64
250d High
$2.64
Next resistance
+27.5%
to 20d High
ROE
-40.2%
Profit margin -147.4%
Dividend Yield
0.00%
P/B 3.8

Lexicon Pharmaceuticals: quick answers

What stage is Lexicon Pharmaceuticals in?

As of Oct 22, 2026, Lexicon Pharmaceuticals (LXRX) is in Stage 3, the topping phase. It entered Stage 3 on Sep 21, 2026 and is in week 5. What the four stages mean

Is Lexicon Pharmaceuticals in an uptrend?

Its uptrend has stalled. Lexicon Pharmaceuticals is in Stage 3, the topping phase that follows an advance. It trades 20.6% below its 200-day average, which is rising.

How far is Lexicon Pharmaceuticals from its 52-week high?

Lexicon Pharmaceuticals closed at $1.49 on Oct 22, 2026, 43.6% below its 52-week high of $2.64. Its 52-week low is $1.14.

How has Lexicon Pharmaceuticals performed over the past year?

As of Oct 22, 2026, Lexicon Pharmaceuticals is up 3.5% over the past year and up 30.7% so far in 2026.

Which sector and industry is Lexicon Pharmaceuticals in?

Lexicon Pharmaceuticals is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company develops sotagliflozin, an orally-delivered small molecule drug for the treatment of hypertrophic cardiomyopathy, and ZYNQUISTA (sotagliflozin) for the treatment of type 1 diabetes. It also commercializes INPEFA (sotagliflozin), a once-daily oral tablet to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, CKD, and other cardiovascular risk factors. In addition, the company develops LX9851, an orally-delivered small molecule drug candidate for the treatment of obesity and associated cardiometabolic disorders, and pilavapadin (LX9211), an orally-delivered small molecule drug candidate for the treatment of neuropathic pain. It has strategic collaboration and license agreements with Viatris Inc. and Bristol-Myers Squibb Company. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.

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All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.