Skip to main content
Indian stocks: Visit www.stage2stocks.com →

Aptevo Therapeutics Inc.

Stage 4 · Declining · week 15

As of Oct 22, 2026, Aptevo Therapeutics is in Stage 4, the downtrend phase, now in week 15 (since Jul 9, 2026). It closed at $1.61, 94.3% below its 52-week high and below its 200-day average, which is falling.

Aptevo Therapeutics Inc., a clinical-stage research and development biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. More about the company

$1.61
+0.63% today
$2.9M · Micro cap
Market Neutral — Building

Pro read

Pro

Our read

Declining, below its long-term trend

Setup score

—

Momentum

Steady

Edge

—

Is APVO early, or has it already run? Pro answers that for every US stock we cover, after every close.

Get Pro · $19 a month

Renews monthly until you cancel. Cancel any time in Plan & billing.

Loading price chart…
Stage Cycle Timeline2023-08-16 → 2026-10-22
S4 69w
S4 75w
S4 15w
2023-08-162026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S4 69w → S1 3w → S4 75w → S1 4w → S4 15w current
Total tracked: 166 weeks across 5 stage runs.

APVO among Biotechnology530th of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…530APVOStage 4 · wk 155−14.8%
vs 52W High
-94.3%
$1.60 lo$28.08 hi
94.3% below 52W high, deep Stage 4 damage
In Stage 4, distance from the 52-week high reflects an ongoing decline, not a discount.
Stage Maturity
Week 15
1w13w26w
Week 15, established downtrend
How long this stock has been in Stage 4 decline. The longer the downtrend, the more entrenched the selling pressure. No length of decline marks a bottom on its own.
vs 200 DMA
-65.0%
200 DMA: $4.60 · sloping down
In Stage 4, the stock is below its 200-day average, the hallmark of a downtrend. Stage analysis waits for that to reverse before buying.
Rel Volume
0.05x
vs 50-day avg
High volume on down days in Stage 4 confirms institutional selling. Low-volume bounces are typical. They lack real buyers and are easy to mistake for reversals.
Trend Health
↓
Short-term trend rolling over
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
-14.8%
3M
-63.3%
6M
-67.0%
YTD
-82.9%
1Y
-94.3%
Scan Membership
Breakout Watch
Latest: 2020-11-06
2 appearances in last 60 days. First seen: 2020-07-27.
A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.
Recent Stage Timeline
2026-10-22S4
Wk 15 · Vol 0.05x
2026-10-21S4
Wk 15 · Vol 0.07x
2026-10-20S4
Wk 15 · Vol 0.11x
2026-10-19S4
Wk 15 · Vol 0.07x
2026-10-16S4
Wk 15 · Vol 0.27x
2026-10-15S4
Wk 14 · Vol 0.09x
2026-10-14S4
Wk 14 · Vol 0.19x
2026-10-13S4
Wk 14 · Vol 0.76x
2026-10-12S4
Wk 14 · Vol 2.62x
2026-10-09S4
Wk 14 · Vol 0.06x
2026-10-08S4
Wk 13 · Vol 0.25x
2026-10-07S4
Wk 13 · Vol 0.11x
Moving averages & range
50 DMA
$2.04
200 DMA
$4.60
52W High
$28.08
52W Low
$1.60
5D Low
$1.60
Resistance levels (recent highs)
20d High
$1.91
60d High
$4.19
120d High
$5.45
250d High
$28.08
Next resistance
+18.6%
to 20d High
P/E (TTM)
0.0
Forward -0.2
ROE
-420.3%
Profit margin 0.0%
Dividend Yield
0.00%
P/B 0.4

Aptevo Therapeutics: quick answers

What stage is Aptevo Therapeutics in?

As of Oct 22, 2026, Aptevo Therapeutics (APVO) is in Stage 4, the downtrend phase. It entered Stage 4 on Jul 9, 2026 and is in week 15. What the four stages mean

Is Aptevo Therapeutics in an uptrend?

No. Aptevo Therapeutics is in a Stage 4 downtrend. It trades 65.0% below its 200-day average, which is falling.

How far is Aptevo Therapeutics from its 52-week high?

Aptevo Therapeutics closed at $1.61 on Oct 22, 2026, 94.3% below its 52-week high of $28.08. Its 52-week low is $1.60.

How has Aptevo Therapeutics performed over the past year?

As of Oct 22, 2026, Aptevo Therapeutics is down 94.3% over the past year and down 82.9% so far in 2026.

Which sector and industry is Aptevo Therapeutics in?

Aptevo Therapeutics is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Aptevo Therapeutics Inc., a clinical-stage research and development biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. The company develops its products using ADAPTIR and ADAPTIR-FLEX platforms to generate monospecific, bispecific, and multi-specific antibody candidates capable of enhancing the human immune system against cancer cells. Its lead clinical blood cancer candidate is mipletamig that is in Phase 1b/2 clinical trial for the treatment of acute myelogenous leukemia. The company also develops ALG.APV-527, a novel investigational bispecific ADAPTIR candidate that is in Phase 1 clinical trial for the treatment malignant pleural mesothelioma, non-small cell lung, gastric/gastro-esophageal, head and neck squamous cell carcinoma, pancreatic, renal, ovarian, prostate, breast, cervical, colorectal, endometrial, and bladder cancers; APVO603, a preclinical dual agonist bispecific ADAPTIR candidate to treat multiple solid tumors; APVO442, a preclinical bispecific candidate based on the ADAPTIR-FLEX platform technology for the treatment of multiple solid tumors; and APVO711, a preclinical dual mechanism bispecific ADAPTIR candidate to treat prostate cancer. It has a collaboration and option agreement with Alligator Bioscience AB to develop ALG.APV-527. Aptevo Therapeutics Inc. was incorporated in 2016 and is headquartered in Seattle, Washington.

Visit company website →

All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.