Skip to main content
Indian stocks: Visit www.stage2stocks.com →

Agios Pharmaceuticals, Inc.

Stage 3 · Topping · week 6

As of Oct 22, 2026, Agios Pharmaceuticals is in Stage 3, the topping phase, now in week 6 (since Sep 16, 2026). It closed at $37.19, 18.2% below its 52-week high and above its 200-day average, which is rising.

Agios Pharmaceuticals, Inc., a biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. More about the company

$37.19
+0.03% today
$2.2B · Mid cap
Market Neutral — Building

Pro read

Pro

Our read

Topping: the uptrend is tiring

Setup score

—

Momentum

Steady

Edge

—

Is AGIO early, or has it already run? Pro answers that for every US stock we cover, after every close.

Get Pro · $19 a month

Renews monthly until you cancel. Cancel any time in Plan & billing.

Loading price chart…
Stage Cycle Timeline2023-08-16 → 2026-10-22
S2 31w
S4 19w
S2 14w
2023-08-162026-10-22
S1S2S3S4Setup score (0–10, dashed line at 5)
S2 5w → S3 3w → S4 13w → S1 8w → S2 31w → S3 4w → S2 8w → S3 4w → S4 19w → S1 9w → S2 14w → S3 4w → S4 9w → S1 10w → S4 7w → S1 2w → S2 9w → S3 5w current
Total tracked: 165 weeks across 18 stage runs.

AGIO among Biotechnology229th of 591 by relative strength

All 591 →
Stocks in Biotechnology ranked by relative strength, with stage and one-month change
#StockStageRS1M
1GTBPStage 2 · wk 799−22.3%
2IOVAStage 2 · wk 1899+38.8%
3SLSStage 3 · wk 499−1.5%
4MRNAStage 2 · wk 1799+11.3%
5TWSTStage 2 · wk 3999−14.5%
6KODStage 2 · wk 499+172.1%
7ERASStage 3 · wk 599+0.7%
8CLYMStage 3 · wk 399−15.8%
…229AGIOStage 3 · wk 643+8.8%
vs 52W High
-18.2%
$22.34 lo$45.49 hi
18.2% below 52W high, weakening from peak
The stock is rolling over from its 52-week high. In Stage 3 distribution, new long positions carry high risk.
Stage Maturity
Week 6
1w13w26w
Week 6, distribution
How long this stock has been in Stage 3 distribution. Longer tops often precede deeper Stage 4 declines.
vs 200 DMA
18.2%
200 DMA: $31.46 · rising
Stock is losing its 200 DMA. Once lost, it confirms Stage 4 risk. This is a major red flag for existing holders.
Rel Volume
0.89x
vs 50-day avg
Volume spikes on down days during Stage 3 signal distribution, with institutions exiting. Stage analysis reads that as a warning against new long positions.
Trend Health
→
Short-term trend flat
Two reads of momentum. The arrow shows the direction of the short-term trend: rising (↑ or ↗), flat (→) or rolling over (↓). The ⇈ mark appears when our trend model reads the move as gaining speed on top of the longer trend. Strongest when both agree.
1M
+8.8%
3M
+2.3%
6M
+44.5%
YTD
+36.8%
1Y
-14.4%
Scan Membership
Breakout Watch
Latest: 2024-11-07
8 appearances in last 60 days. First seen: 2020-01-23.
A stock that keeps qualifying week after week does so because its Stage 2 structure keeps holding. Staying power in the scan says more about the trend than any single appearance.
Recent Stage Timeline
2026-10-22S3
Wk 6 · Vol 0.89x
2026-10-21S3
Wk 6 · Vol 0.64x
2026-10-20S3
Wk 5 · Vol 1.45x
2026-10-19S3
Wk 5 · Vol 1.91x
2026-10-16S3
Wk 5 · Vol 0.92x
2026-10-15S3
Wk 5 · Vol 2.02x
2026-10-14S3
Wk 5 · Vol 0.91x
2026-10-13S3
Wk 4 · Vol 1.15x
2026-10-12S3
Wk 4 · Vol 0.62x
2026-10-09S3
Wk 4 · Vol 0.76x
2026-10-08S3
Wk 4 · Vol 1.93x
2026-10-07S3
Wk 4 · Vol 1.58x
Moving averages & range
50 DMA
$33.34
200 DMA
$31.46
52W High
$45.49
52W Low
$22.34
5D Low
$31.32
Resistance levels (recent highs)
20d High
$37.19
60d High
$37.19
120d High
$44.01
250d High
$45.49
Next resistance
+18.3%
to 120d High
ROE
-34.3%
Profit margin 0.0%
Dividend Yield
0.00%
P/B 2.2

Agios Pharmaceuticals: quick answers

What stage is Agios Pharmaceuticals in?

As of Oct 22, 2026, Agios Pharmaceuticals (AGIO) is in Stage 3, the topping phase. It entered Stage 3 on Sep 16, 2026 and is in week 6. What the four stages mean

Is Agios Pharmaceuticals in an uptrend?

Its uptrend has stalled. Agios Pharmaceuticals is in Stage 3, the topping phase that follows an advance. It trades 18.2% above its 200-day average, which is rising.

How far is Agios Pharmaceuticals from its 52-week high?

Agios Pharmaceuticals closed at $37.19 on Oct 22, 2026, 18.2% below its 52-week high of $45.49. Its 52-week low is $22.34.

How has Agios Pharmaceuticals performed over the past year?

As of Oct 22, 2026, Agios Pharmaceuticals is down 14.4% over the past year and up 36.8% so far in 2026.

Which sector and industry is Agios Pharmaceuticals in?

Agios Pharmaceuticals is in the Biotechnology industry, part of the Health Care sector.

About this companyHealth Care· Biotechnology

Agios Pharmaceuticals, Inc., a biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. Its lead product includes PYRUKYND (mitapivat), an activator of wild-type and mutant pyruvate kinase (PK), enzymes used for the treatment of hemolytic anemias in adults with PK deficiency. The company's PYRUKYND product is also used for the treatment of sickle cell disease that is in phase 3 clinical trial; for the treatment of PK deficiency in pediatric patients; and AQVESME for the treatment of adult patients with non-transfusion dependent and transfusion-dependent alpha- or beta-thalassemia. In addition, it developed tebapivat, a PK activator for the treatment of lower-risk myelodysplastic syndrome and sickle cell disease; AG-181, a phenylalanine hydroxylase stabilizer for the treatment of phenylketonuria (PKU); and AG-236, an siRNA in-licensed from Alnylam, targeting the transmembrane serine protease 6 (TMPRSS6) gene for the treatment of polycythemia vera. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.

Visit company website →

All analytics based on EOD data. Data as of 2026-10-22. Past data patterns are not indicative of future results. This page is a data analytics tool only.